delivery,?HSP,?targeting drug?conjugate

By Targets:	ADC Antibody (15) ADC Cytotoxin (51) ADC Linker (667) ALCAM/CD166 (1) Amino Acid Derivatives (1) Antibody-Drug Conjugates (ADCs) (29) Apoptosis (9) Bacterial (4) Bcl-2 Family (1) c-Met/HGFR (1) CD19 (1) CD22 (1) CD276/B7-H3 (1) DNA Alkylator/Crosslinker (8) DNA/RNA Synthesis (1) Drug Metabolite (2) Drug-Linker Conjugates for ADC (43) EGFR (9) Glucocorticoid Receptor (1) Isotope-Labeled Compounds (3) Kinesin (1) Mesothelin (1) Microtubule/Tubulin (17) Mitochondrial Metabolism (1) NAMPT (1) Nectin-4 (2) Notch (1) Nucleoside Antimetabolite/Analog (1) PD-1/PD-L1 (3) PROTAC Linkers (203) STING (3) TAM Receptor (3) TNF Receptor (2) Toll-like Receptor (TLR) (2) Topoisomerase (17) TROP2 (1)
By Research Areas:	Cancer (831) Cardiovascular Disease (1) Infection (8) Inflammation/Immunology (33)
Click Chemistry:	ADC Synthesis (229) TCO (15) DBCO (49) PROTAC Synthesis (54) Azide (79) BCN (22) Tetrazine (30) Alkynes (43)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132258A

Mirvetuximab soravtansine (solution) IMGN853 (solution)	Antibody-Drug Conjugates (ADCs)	Cancer
Mirvetuximab soravtansine (IMGN853) solution is an antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A. Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage .

HY-129365

SNPB

ADC Linker Cancer

SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

SNPB	ADC Linker	Cancer
SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

HY-132258

Mirvetuximab soravtansine IMGN853	Antibody-Drug Conjugates (ADCs)	Cancer
Mirvetuximab soravtansine (IMGN853) is an antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A. Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage .

HY-160182

INX-P

ADC Linker Glucocorticoid Receptor Inflammation/Immunology

INX-P is glucocorticosteroid-target antibody drug conjugate (ADC) .

INX-P	ADC Linker Glucocorticoid Receptor	Inflammation/Immunology
INX-P is glucocorticosteroid-target antibody drug conjugate (ADC) .

HY-P2548

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated	EGFR	Others
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification .

HY-129376

Sulfo-SNPB

ADC Linker Cancer

Sulfo-SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-126498

PDEC-NB

ADC Linker Cancer

PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
HY-126519

PDdEC-NB

ADC Linker Cancer

PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
HY-42146

BMPS

ADC Linker Cancer

BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-12448

SPDB

ADC Linker Cancer

SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
HY-129375

SNPB-sulfo-Me

ADC Linker Cancer

SNPB-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-126667

SC-Val-Cit-PAB

ADC Linker Cancer

SC-Val-Cit-PAB is a cleavable ADC linker for antibody-drug conjugates (ADCs).
HY-129366

PDB-Pfp

ADC Linker Cancer

PDB-Pfp is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
HY-129368

SPDMV

ADC Linker Cancer

SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
HY-129369

SPDMB

ADC Linker Cancer

SPDMB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
HY-129373

SPDMV-sulfo

ADC Linker Cancer

SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
HY-44235

MC-Gly-Gly-Phe

ADC Linker Cancer

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
HY-126530

PPC-NB

ADC Linker Cardiovascular Disease Cancer

PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC) .
HY-128927

Mc-Leu-Gly-Arg

ADC Linker Cancer

Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.
HY-128970

Mp-polymer ester

ADC Linker Cancer

Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-129370

SPDB-sulfo

ADC Linker Cancer

SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
HY-126531

DMAC-PDB

ADC Linker Cancer

DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-114697

DSG Crosslinker

Disuccinimidyl glutarate
ADC Linker Inflammation/Immunology

DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Sulfo-SNPB	ADC Linker	Cancer
Sulfo-SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

PDEC-NB	ADC Linker	Cancer
PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).

PDdEC-NB	ADC Linker	Cancer
PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).

BMPS	ADC Linker	Cancer
BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

SPDB	ADC Linker	Cancer
SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .

SNPB-sulfo-Me	ADC Linker	Cancer
SNPB-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC).

SC-Val-Cit-PAB	ADC Linker	Cancer
SC-Val-Cit-PAB is a cleavable ADC linker for antibody-drug conjugates (ADCs).

PDB-Pfp	ADC Linker	Cancer
PDB-Pfp is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

SPDMV	ADC Linker	Cancer
SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .

SPDMB	ADC Linker	Cancer
SPDMB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .

SPDMV-sulfo	ADC Linker	Cancer
SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).

MC-Gly-Gly-Phe	ADC Linker	Cancer
MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

PPC-NB	ADC Linker	Cardiovascular Disease Cancer
PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC) .

Mc-Leu-Gly-Arg	ADC Linker	Cancer
Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.

Mp-polymer ester	ADC Linker	Cancer
Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

SPDB-sulfo	ADC Linker	Cancer
SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .

DMAC-PDB	ADC Linker	Cancer
DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

DSG Crosslinker Disuccinimidyl glutarate	ADC Linker	Inflammation/Immunology
DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-118759

DSP Crosslinker 1 Publications Verification	ADC Linker	Inflammation/Immunology
DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs) .

HY-140098

Boc-Cystamine

ADC Linker Cancer

Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-140014

Val-Cit

ADC Linker Cancer

Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-126349

DTSSP Crosslinker

ADC Linker Cancer

DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-101151

sulfo-SPDB

ADC Linker Cancer

sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-130111

DMAC-SPP

ADC Linker Cancer

DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-126405

SMPT

ADC Linker Cancer

SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Boc-Cystamine	ADC Linker	Cancer
Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Val-Cit	ADC Linker	Cancer
Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

DTSSP Crosslinker	ADC Linker	Cancer
DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

sulfo-SPDB	ADC Linker	Cancer
sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

DMAC-SPP	ADC Linker	Cancer
DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

SMPT	ADC Linker	Cancer
SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W071006

PPC-NHS ester 2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate	ADC Linker	Cancer
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-133540

Maleimide-DOTA 1 Publications Verification Maleimido-mono-amide-DOTA	ADC Linker	Inflammation/Immunology Cancer
Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-133542

Dimethylamine-SPDB

ADC Linker Cancer

Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-133543

SPDP-sulfo

ADC Linker Cancer

SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-133550

DMAC-SPDB

ADC Linker Cancer

DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-150043A

MDTF

ADC Linker Cancer

MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-160157

IM-2

Drug-Linker Conjugates for ADC Cancer

IM-2 is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-20560

(Ac)Phe-Lys(Alloc)-PABC-PNP

ADC Linker Cancer

(Ac)Phe-Lys(Alloc)-PABC-PNP is an useful cleavable chemical linker in antibody drug conjugates.
HY-128929

Fmoc-PEA

ADC Linker Cancer

Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC) .
HY-129352

Cbz-Phe-(Alloc)Lys-PAB-PNP

ADC Linker Cancer

Cbz-Phe-(Alloc)Lys-PAB-PNP is an cleavable linker for antibody-drug conjugates (ADC) design.
HY-129367

NO2-SPP

ADC Linker Cancer

NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).
HY-130099

Ald-Ph-amido-PEG2

ADC Linker Cancer

Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate .
HY-129353

Boc-Phe-(Alloc)Lys-PAB-PNP

ADC Linker Cancer

Boc-Phe-(Alloc)Lys-PAB-PNP is a used as a cleavable linker for antibody-drug conjugates (ADC).
HY-129360

Ala-Ala-Asn-PAB

ADC Linker Cancer

Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs) .
HY-126496

PEG4-SPDP

ADC Linker Cancer

PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
HY-140129

NHS-SS-biotin

ADC Linker Cancer

NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-140096

Aminoethyl-SS-propionic acid

ADC Linker Cancer

Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-140987

5-Maleimidovaleric acid

ADC Linker Cancer

5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-140122

THP-SS-alcohol

ADC Linker Cancer

THP-SS-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-126495A

Sulfo-LC-SPDP sodium

ADC Linker Cancer

Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Dimethylamine-SPDB	ADC Linker	Cancer
Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

SPDP-sulfo	ADC Linker	Cancer
SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

DMAC-SPDB	ADC Linker	Cancer
DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

MDTF	ADC Linker	Cancer
MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

IM-2	Drug-Linker Conjugates for ADC	Cancer
IM-2 is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

(Ac)Phe-Lys(Alloc)-PABC-PNP	ADC Linker	Cancer
(Ac)Phe-Lys(Alloc)-PABC-PNP is an useful cleavable chemical linker in antibody drug conjugates.

Fmoc-PEA	ADC Linker	Cancer
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC) .

Cbz-Phe-(Alloc)Lys-PAB-PNP	ADC Linker	Cancer
Cbz-Phe-(Alloc)Lys-PAB-PNP is an cleavable linker for antibody-drug conjugates (ADC) design.

NO2-SPP	ADC Linker	Cancer
NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).

Ald-Ph-amido-PEG2	ADC Linker	Cancer
Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate .

Boc-Phe-(Alloc)Lys-PAB-PNP	ADC Linker	Cancer
Boc-Phe-(Alloc)Lys-PAB-PNP is a used as a cleavable linker for antibody-drug conjugates (ADC).

Ala-Ala-Asn-PAB	ADC Linker	Cancer
Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs) .

PEG4-SPDP	ADC Linker	Cancer
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).

NHS-SS-biotin	ADC Linker	Cancer
NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Cat. No.	Product Name

HY-L023

Toxins for Antibody-Drug Conjugate Research Library

94 compounds

Antibody-Drug Conjugates (ADCs), a new class of treatment for cancer, are composed with a monoclonal antibody, a linker and a cytotoxic agent also referred to as a payload. To date, several ADCs have received market approval and more than 60 ADCs are currently in clinical trials. ADCs are one of the fastest growing classes of oncology drugs worldwide.

The payload or cytotoxic agent is the most important unit in the ADC. ADC has the capability to kill cancer cell depending on the potency of the payload. MCE provides 94 highly potent cytotoxins that contain auristatin derivatives, maytansinoids, calicheamicin, duocarmycin, pyrrolobenzodiazepines (PBDs), etc.

Cat. No.	Product Name	Type

HY-126851

Fluorescein-DBCO	Dyes
Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fluorescein-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-123687

DBCO-Sulfo-NHS ester sodium	Dyes
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-78921AG

Fmoc-3VVD-OH (GMP)

Fluorescent Dye

Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-78932G

Dap-NE hydrochloride (GMP)	Fluorescent Dye
Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs) .

HY-131833G

Fmoc-Gly-Gly-Phe-OH (GMP)	Fluorescent Dye
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-20336G

Mc-Val-Cit-PABC-PNP (GMP)	Fluorescent Dye
Mc-Val-Cit-PABC-PNP GMP is a GMP grade Mc-Val-Cit-PABC-PNP (HY-20336). Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-44980G

Fmoc-Gly-NH-CH2-acetyloxy (GMP)	Fluorescent Dye
Fmoc-Gly-NH-CH2-acetyloxy GMP is a GMP grade Fmoc-Gly-NH-CH2-acetyloxy (HY-44980). Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).

HY-78931G

Boc-Dap-NE (GMP)	Fluorescent Dye
Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-15579G

MMAF (GMP) Monomethylauristatin F (GMP)	Fluorescent Dye
MMAF (Monomethylauristatin F) GMP is a GMP grade MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A .

HY-15579BG

MMAF sodium (GMP) Monomethylauristatin F sodium (GMP)	Fluorescent Dye
MMAF sodium GMP is a GMP grade MMAF (sodium) (HY-15579B). MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A .

HY-W000423G

DBCO-amine (GMP)	Fluorescent Dye
DBCO-amine GMP is a GMP grade DBCO-amine (HY-W000423). DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-amine is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-15578G

McMMAF (GMP) Maleimidocaproyl monomethylauristatin F (GMP)	Fluorescent Dye
McMMAF GMP is a GMP grade McMMAF (HY-15578). McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for *antibody-drug conjugates* (ADC)**. McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent .

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)	Fluorescent Dye
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Cat. No.	Product Name	Type

HY-78921AG

Fmoc-3VVD-OH (GMP)

Biochemical Assay Reagents

Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-78932G

Dap-NE hydrochloride (GMP)	Biochemical Assay Reagents
Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs) .

HY-131833G

Fmoc-Gly-Gly-Phe-OH (GMP)	Biochemical Assay Reagents
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-20336G

Mc-Val-Cit-PABC-PNP (GMP)	Biochemical Assay Reagents
Mc-Val-Cit-PABC-PNP GMP is a GMP grade Mc-Val-Cit-PABC-PNP (HY-20336). Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-44980G

Fmoc-Gly-NH-CH2-acetyloxy (GMP)	Biochemical Assay Reagents
Fmoc-Gly-NH-CH2-acetyloxy GMP is a GMP grade Fmoc-Gly-NH-CH2-acetyloxy (HY-44980). Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).

HY-78931G

Boc-Dap-NE (GMP)	Biochemical Assay Reagents
Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-15579G

MMAF (GMP) Monomethylauristatin F (GMP)	Biochemical Assay Reagents
MMAF (Monomethylauristatin F) GMP is a GMP grade MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A .

HY-15579BG

MMAF sodium (GMP) Monomethylauristatin F sodium (GMP)	Biochemical Assay Reagents
MMAF sodium GMP is a GMP grade MMAF (sodium) (HY-15579B). MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A .

HY-W000423G

DBCO-amine (GMP)	Biochemical Assay Reagents
DBCO-amine GMP is a GMP grade DBCO-amine (HY-W000423). DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-amine is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-15578G

McMMAF (GMP) Maleimidocaproyl monomethylauristatin F (GMP)	Biochemical Assay Reagents
McMMAF GMP is a GMP grade McMMAF (HY-15578). McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for *antibody-drug conjugates* (ADC)**. McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent .

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)	Biochemical Assay Reagents
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Cat. No.	Product Name	Target	Research Area

HY-P10069

Ac-pSar12-OH

Peptides Others

Ac-pSar12-OH, as a linker, can be used for preparation of Ligand-Drug-Conjugate (LDC) .
HY-136432

Mc-Gly-Gly-Phe-Gly-PAB-OH

Mc-GGFG-PAB-OH
ADC Linker Cancer

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-P1449

Boc-Gly-Gly-Phe-Gly-OH	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-136432A

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA

Mc-GGFG-PAB-OH TFA
ADC Linker Cancer

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-P2548

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated	EGFR	Others
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification .

HY-P1449A

Boc-Gly-Gly-Phe-Gly-OH TFA	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-P4166

Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar	Peptides	Cancer
Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar is a decapeptide. Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar can be used to preparation of antibody-drug conjugate .

HY-P4073

ANG1005 GRN1005; Paclitaxel trevatide	Antibody-Drug Conjugates (ADCs)	Cancer
ANG1005 (Paclitaxel trevatide) is a brain-penetrating peptide-drug conjugate. ANG1005, a taxane derivative, consists of three paclitaxel (HY-B0015) molecules covalently linked to Angiopep-2, designed to cross the blood-brain and blood-cerebrospinal barriers and to penetrate malignant cells via low density lipoprotein receptor-related protein (LRP1) transport system .

Cat. No.	Product Name	Target	Research Area

HY-P99016B

Enfortumab vedotin-ejfv (solution)	Antibody-Drug Conjugates (ADCs) Nectin-4	Cancer
Enfortumab vedotin-ejfv (solution) is an anti-Nectin-4 antibody-drug conjugate for the management of urothelial carcinoma .

HY-P99360

Enapotamab Anti-AXL/UFO Reference Antibody (enapotamab)	TAM Receptor	Cancer
Enapotamab is an anti-AXL/UFO reference antibody. Enapotamab can be used to synthesis Bcl-xl inhibitor antibody-drug conjugates .

HY-P9980

Belantamab GSK2857914	TNF Receptor ADC Antibody	Cancer
Belantamab (GSK2857914) is a humanised IgG1 anti-BCMA (TNFRSF17) monoclonal antibody. Belantamab can be used in the synthesis of antibody-drug conjugate (ADC), Belantamab mafodotin .

HY-P99718

Lupartumab BAY 1112623	ADC Antibody	Cancer
Lupartumab (BAY 1112623) is an anti-LYPD3 (C4.4A) monoclonal antibody that can be used for the synthesis of antibody-drug conjugate BAY 1129980 .

HY-P99593

Sofituzumab vedotin DMUC5754A	Antibody-Drug Conjugates (ADCs)	Cancer
Sofituzumab vedotin (DMUC5754A) is a MMAE-containing anti-MUC16 antibody-drug conjugate (ADC) with a protease-cleavable linker. Sofituzumab vedotin can be used for the research of cancer .

HY-P99854

Disitamab RC48-0	EGFR ADC Antibody	Cancer
Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (Disitamab vedotin (HY-P9985)) .

HY-141598

Datopotamab deruxtecan DS-1062; Dato-DXd	Antibody-Drug Conjugates (ADCs) Topoisomerase	Cancer
Datopotamab deruxtecan (DS-1062; Dato-DXd) is a *trophoblast cell surface antigen 2 (TROP2)-directed antibody-drug conjugate* (ADC)**. Datopotamab deruxtecan has a potent antitumor activity .

HY-P99788

Praluzatamab	ADC Antibody ALCAM/CD166	Cancer
Praluzatamab is a monoclonal antibody targeting the activated leukocyte cell adhesion molecule (ALCAM/CD116). Praluzatamab can be used to synthesize Praluzatamab ravtansine (antibody-drug conjugates). Praluzatamab can be used for research of cancers .

HY-P99352

Anetumab Anti-MSLN Antibody	Mesothelin	Cancer
Anetumab (Anti-MSLN Antibody) is an anti-mesothelin (MSLN) antibody. MSLN is a tumor-associated antigen. Anetumab can be used to synthesis Anetumab ravtansine, a MSLN-targeting antibody-drug conjugate (ADC). Anetumab can be used for the research of malignant tumor .

HY-P99101

Vobramitamab AEX-4089	ADC Antibody	Cancer
Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018 .

HY-P99054

Tusamitamab	Inhibitory Antibodies	Cancer
Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative) .

HY-P99967

Cantuzumab	ADC Antibody	Cancer
Cantuzumab is a monoclonal antibody that can binds the CanAg antigen. Cantuzumab is typically linked to one of several cytotoxic agents, yielding antibody-drug conjugates (ADC), such as Cantuzumab mertansine (HY-P99492) and Cantuzumab ravtansine (HY-P99493) .

HY-P99043

Rovalpituzumab	Notch	Cancer
Rovalpituzumab is a humanized monoclonal antibody against delta-like protein 3 (DLL3). Rovalpituzumab can be used in the synthesis of antibody-drug conjugate (ADC), Rovalpituzumab Tesirine . Rovalpituzumab has activity against small cell lung cancer (SCLC) .

HY-P99734

Mipasetamab uzoptirine ADCT-601	TAM Receptor	Cancer
Mipasetamab uzoptirine (ADCT-601) is an *AXL*-targeted *antibody-drug conjugates* (ADCs)**. Mipasetamab uzoptirine consists of a humanized anti-AXL antibody, a cleavable linker and the potent pyrrolobenzodiazepine (PBD) dimer cytotoxin SG3199. Mipasetamab uzoptirine can be used for the research of cancers .

HY-P99733

Mipasetamab	ADC Antibody TAM Receptor	Cancer
Mipasetamab is an IgG1κ antibody targeting to AXL, a tyrosine kinase receptor and an TAM Receptor. Mipasetamab involves in synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted *antibody-drug conjugate* (ADC)**. ADCT-601 has anti-tumor activity .

HY-P99593A

Sofituzumab vedotin (solution) DMUC5754A (solution)	Antibody-Drug Conjugates (ADCs)	Cancer
Sofituzumab vedotin (DMUC5754A) (solution) is an antibody-drug conjugate (ADC) that contains the humanized IgG1 anti-MUC16 monoclonal antibody and a potent anti-mitotic agent, monomethyl auristatin E (MMAE), linked through a protease-cleavable linker .

HY-P99970

Lifastuzumab	ADC Antibody	Others
Lifastuzumab is a humanized anti-NaPi2b monoclonal antibody (IgG1 type). Lifastuzumab can be coupled with monomethyl auristatin E (MMAE) through ADC Linker to form an antibody-drug conjugate (ADC) lifastuzumab vedotin (DNIB0600A) with anticancer activity .

HY-P99042

Polatuzumab	ADC Antibody	Cancer
Polatuzumab is a monoclonal antibody, which targets CD79b that is found on the surface of B cells. Polatuzumab sticks to the CD79b protein and delivers the chemotherapy compound into the cell. Polatuzumab can be used to synthesize Polatuzumab Vedotin, which is an antibody-drug conjugate (ADC) targeting CD79b .

HY-P99264

Inotuzumab Humanized Anti-CD22 Recombinant Antibody	ADC Antibody CD22	Cancer
Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) is a humanized IgG4, κ antibody that targets human CD22. Inotuzumab can be linked to a toxic agent ozogamicin as an antibody-drug conjugate (ADC). Inotuzumab can be used for the research of acute lymphoblastic leukemia and non-Hodgkin lymphoma .

HY-P99285

Denintuzumab hBU 12	ADC Antibody CD19	Others
Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab can be used as the antibody moiety (ADC antibody) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia .

HY-132253

Polatuzumab vedotin	Antibody-Drug Conjugates (ADCs)	Cancer
Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. Polatuzumab vedotin has the potential for the research of Large B-cell lymphomas (LBCL) .

HY-P99682

Ladiratuzumab hLIV22	Inhibitory Antibodies	Cancer
Ladiratuzumab (hLIV22) is an anti-LIV-1/ZIP6 humanized monoclonal antibody. Ladiratuzumab, conjugated with the microtubule disrupting agent, MMAE (HY-15162) to compose SGN-LIV1A, an *antibody-drug conjugate* (ADC)**. Ladiratuzumab can be used for research of breast cancer .

HY-P99843

Datopotamab	TROP2 ADC Antibody	Cancer
Datopotamab (CDP7657) is an antibody targeting to TROP2. Datopotamab can be used to synthesize Datopotamab deruxtecan (HY-141598), TROP2-directed antibody-drug conjugate (ADC). Datopotamab deruxtecan consists of DNA topoisomerase I inhibitor Deruxtecan (HY-13631E) and Datopotamab .

HY-P99349

Loncastuximab tesirine Loncastuximab tesirine-lpyl; ADCT-402	Antibody-Drug Conjugates (ADCs) Apoptosis	Cancer
Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma .

HY-P99656

Iladatuzumab MCDS0593A	ADC Antibody	Cancer
Iladatuzumab (MCDS0593A) is a humanized IgG1 anti-human CD79B monoclonal antibody. Iladatuzumab can be used to synthesize antibody-drug conjugates (ADC) Iladatuzumab vedotin (DCDS0780A; HY-P99657), which has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research .

HY-P99813

Patritumab deruxtecan HER3-DXd	Antibody-Drug Conjugates (ADCs)	Cancer
Patritumab deruxtecan (HER3-DXd) is an antibody-drug conjugate (ADC) consisting of a fully human anti-HER3 IgG1 monoclonal antibody Patritumab (HY-P99275) attached to a topoisomerase I inhibitor payload via a tetrapeptide-based cleavable linker. Patritumab deruxtecan shows anticancer activity .

HY-P99956

Zilovertamab vedotin VLS-101; MK-2140	Antibody-Drug Conjugates (ADCs) Apoptosis	Cancer
Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate comprising the humanized monoclonal antibody zilovertamab and and the anti-microtubule cytotoxin monomethyl vedotin. Zilovertamab vedotin binding to tumor cell ROR1 results in rapid internalization, trafficking to lysosomes, antibody–agent conjugate cleavage, and monomethyl vedotin release. Zilovertamab vedotin induces apoptosis. Zilovertamab vedotin can be used in research of cancer .

HY-P99740

Mirzotamab	CD276/B7-H3	Cancer
Mirzotamab is an IgG1κ antibody targeting to CD276/B7-H3. Mirzotamab can conjugates with Clezutoclax (HY-137774), an BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted *antibody drug conjugate* (ADC)** .

HY-P99971

Gemtuzumab	ADC Antibody	Cancer
Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia .

HY-P99612

Farletuzumab ecteribulin MORAb-202	Antibody-Drug Conjugates (ADCs)	Cancer
Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.

HY-P990027

Izeltabart	ADC Antibody	Cancer
Izeltabart is a high-affinity humanized antibody targeting ADAM9. Izeltabart can be used as ADC Antibody for site-specific conjugation with Maytansinoid-based DM21-C (a Drug-Linker Conjugates for ADC), to synthesize IMGC936 (Antibody-Drug Conjugates (ADCs)) with strong anti-cancer activity. DM21-C is composed of Maytansinoid (microtubule inhibitor) and a stable tripeptide linker. IMGC936 exhibits cytotoxicity against ADAM9-positive human tumor cell lines and potent antitumor activity in xenograft tumor models .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-117371

Hemiasterlin (-)-Hemiasterlin; Milnamide B	Alkaloids Structural Classification Classification of Application Fields Animals Marine natural products Sponge Disease Research Fields Indole Alkaloids Cancer	ADC Cytotoxin
Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effcts. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs) .

HY-W034918

Docosanedioic acid	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Cancer	ADC Linker PROTAC Linkers
Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-W007324

Maleimide	Alkaloids Microorganisms Pyrrole Alkaloids Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	ADC Linker
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .

Cat. No.	Product Name	Chemical Structure

HY-161022S1

FL118-C3-O-C-amide-C-NH2-d5 formate
FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-15583S

Auristatin F-d8
Auristatin F-d₈ is deuterium labeled Auristatin F (HY-15583). Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .

HY-114816S

N-butyryl-L-Homoserine lactone-d5

N-butyryl-L-Homoserine lactone-d₅ is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].

Cat. No.	Product Name		Classification

HY-120903

DBCO-C3-Acid

DBCO ADC Synthesis

DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker .
HY-145066

Gly-Gly-Gly-PEG4-azide

ADC Synthesis Azide

Gly-Gly-Gly-PEG4-azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
HY-157275

Gly-Gly-Gly-PEG2-azide

Azide ADC Synthesis

Gly-Gly-Gly-PEG2-azide is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs) .
HY-141190

Gly-Gly-Gly-PEG3-TCO

ADC Synthesis TCO

Gly-Gly-Gly-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-141284

Gly-Gly-Gly-PEG4-methyltetrazine		ADC Synthesis Tetrazine
Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-141150

Azido-PEG5-Ala-Ala-Asn-PAB

Azide ADC Synthesis

Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-151764

N3-D-Orn(Boc)-OH		ADC Synthesis Azide
N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) .

HY-151764A

N3-D-Orn(Boc)-OH (CHA)		ADC Synthesis Azide
N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) .

HY-141167

TCO-PEG4-NHS ester		TCO PROTAC Synthesis ADC Synthesis
TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-141170

TCO-PEG12-NHS ester		ADC Synthesis TCO PROTAC Synthesis
TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-116270

DBCO-Maleimide		ADC Synthesis DBCO
DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-42973

DBCO-NHS ester 4 Publications Verification		ADC Synthesis DBCO
DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W000423

DBCO-amine		ADC Synthesis DBCO
DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-79584

Propargyl-Tos		Alkynes ADC Synthesis
Propargyl-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-126851

Fluorescein-DBCO		DBCO ADC Synthesis
Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fluorescein-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136095

Tetrazine-biotin		Tetrazine ADC Synthesis
Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-136104

Methyltetrazine-Maleimide		ADC Synthesis Tetrazine
Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-123687

DBCO-Sulfo-NHS ester sodium		DBCO ADC Synthesis
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140306

Mal-Sulfo-DBCO		DBCO ADC Synthesis
Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-Sulfo-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-135977

DBCO-SS-aldehyde		DBCO ADC Synthesis
DBCO-SS-aldehyde is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-aldehyde is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-135972

BCN-SS-amine		BCN ADC Synthesis
BCN-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-amine is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-135973

BCN-SS-NHS		BCN ADC Synthesis
BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-138506

DBCO-S-S-acid		DBCO ADC Synthesis
DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-S-S-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136032

Tetrazine-SS-NHS		Tetrazine ADC Synthesis
Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-136033

Methyltetrazine-SS-NHS		Tetrazine ADC Synthesis
Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-136039

TCO-SS-amine		ADC Synthesis TCO
TCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-SS-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-130928

Tetrazine-Ph-OPSS		ADC Synthesis Tetrazine
Tetrazine-Ph-OPSS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-Ph-OPSS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-136031

Tetrazine-SS-Biotin		ADC Synthesis Tetrazine
Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-130810

DBCO-Sulfo-Link-biotin		DBCO ADC Synthesis
DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-130935

DBCO-Val-Cit-OH		ADC Synthesis DBCO
DBCO-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-133504

Tetrazine-Ph-SS-amine		ADC Synthesis Tetrazine
Tetrazine-Ph-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-Ph-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-130936

DBCO-Val-Cit-PABC-OH		ADC Synthesis DBCO
DBCO-Val-Cit-PABC-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-PABC-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-130937

DBCO-Val-Cit-PABC-PNP		ADC Synthesis DBCO
DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-133412

DBCO-NHCO-S-S-NHS ester		ADC Synthesis DBCO
DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-133413

DBCO-CONH-S-S-NHS ester		DBCO ADC Synthesis
DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-120770

DBCO-PEG4-Maleimide		DBCO ADC Synthesis
DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-135971

BCN-PEG4-acid		BCN ADC Synthesis
BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136125

BCOT-PEF3-OPFP		ADC Synthesis BCN
BCOT-PEF3-OPFP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCOT-PEF3-OPFP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145593

Aminooxy-PEG2-BCN		ADC Synthesis BCN
Aminooxy-PEG2-BCN is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Aminooxy-PEG2-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136046

PTAD-PEG4-alkyne		Alkynes ADC Synthesis
PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PTAD-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-136049

APN-PEG4-DBCO		DBCO ADC Synthesis
APN-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136044

APN-PEG4-BCN		ADC Synthesis BCN
APN-PEG4-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136061

BCN-PEG4-HyNic		BCN ADC Synthesis
BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-HyNic is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136067

DBCO-PEG4-HyNic		DBCO ADC Synthesis
DBCO-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-HyNic is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136075

HyNic-PEG4-alkyne		ADC Synthesis Alkynes
HyNic-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . HyNic-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-136101

Bocaminooxyacetamide-PEG3-alkyne		ADC Synthesis Alkynes
Bocaminooxyacetamide-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Bocaminooxyacetamide-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-115524

DBCO-NHS ester 2		ADC Synthesis DBCO
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry . DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140136

PC DBCO-PEG3-biotin		DBCO ADC Synthesis
PC DBCO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC DBCO-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140930

Diazo Biotin-PEG3-DBCO		DBCO ADC Synthesis
Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Diazo Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140108

Propargyl-PEG1-SS-alcohol		Alkynes ADC Synthesis
Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG1-SS-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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